I always turn on subtitles now that I have a child. Since all toys seem to have some sort of annoying audio I can never hear the tv without pumping up the volume to room rumbling levels. Of course that doesn't sit well with my wife and probably isn't good for my son's delicate ears. Couple that with whisper quiet levels I have to play games at when he is sleeping and subtitleses are a must.
I know Assassin's Creed 3 had subtitles, but I played all the rest before my son was born, so I can't speak to those.
Another issue I sometimes have is inadequate brightness adjusters in game to lighten things up when playing on my tv. I hate changing the brightness on the tv back and forth, but some games force it. The Walking Dead was pretty bad. The scale from 1-10 provided little difference and some dark areas I could literally see nothing.
Ps: by "literally" I mean literally, not figuratively like all the dumb kids use it now.