Secret of Mana definitely! A few more:
Final Fight 2 & 3
and some more obscure titles:
Peacekeepers, Brawl Brothers, Captain Commando, Power Rangers The Movie (all like Final Fight)
Another multiplayer game I really liked was (ok, this sounds weird): Tiny Toons Wacky Sports. Up to 4 could play with the multi-tap. It consisted of maybe 8 or so "sports" events where you could all more or less compete at the same time. It was the "Mario Party" of the time.