The gameplay changes every time. Even FIFA 11 handles very differently than World Cup 2010, which came out like 6 months before.
They seem to be saying they spent a lot of time on the physics/collision engine this time around. I really hope they've made collisions with the keeper (whether on the ground or in-air) more realistic.
I logged an embarassing number of hours on FIFA 11 (especially Ultimate Team), so this is slam-dunk day one purchase for me. Just ordered up. Thanks OP, and thanks to Amazon for matching.
Edit: Also, i keep seeing a September 30th release date for this. Is this *really* releasing on a Friday? Or is this just a place-holder date that everyone seems to be using?