I have to disagree w/ Danimal. If you are looking at those options, I'd easily take Brees there. In fact I'd be surprised if he is there, but you'd be wise to take him at the end of the second. Also, with the exception of CJ take all those other backs off your list for end of the 2nd/top of the 3rd.
I should mention that because I'm personally so dead set against taking a QB that early, I didn't really take the QB's you listed into consideration. But Duo_Maxwell is right- if Brees is still there, by all means take him. He most likely won't be, though. Manning shouldn't still be there, either, but I'd also say grab him if he is. Newton could possibly still be there the next time it comes back around to you, so you could roll the dice and beef up your RB's or WR's with your 2nd and 3rd picks, and hope you can still get Newton later. Or maybe Ryan. But yeah, if one of the top 2 or 3 QB's on the board falls that far, jump on him.
Follow that plan of attack and while you may not win the RB battle every week, but you just may win more games. PLus I think some fairly decent RB2 options like Bush/Miller/Murrary/Gore or Sporles if you want him will def. be there by the time you next set of picks rolls up.
I'll respectfully disagree with this part; I don't think that Bush, Murray, Gore, or even Sproles will still be available by the end of the 4th round. I think Miller will be, but considering it's PPR, there's a chance Bush will go before the end of round 2. Some of these other guys we've been discussing- Fitzgerald, Thomas, Cruz, and Cobb may all go very early, too.
12 team league, we just did the draft selections tonight. My draft is the 25th. I got the 5th pick.... It's a non PPR league.
Idk what to do..
Picking 5th in the 1st round, I'd say definitely go RB. AP will be gone, but you'll have some good ones to choose from. Martin, Foster, Charles, Lynch, Spiller, Richardson, Morris, depending on who's left, I think any of those guys is a solid 1st pick. After that, it depends on your league's scoring system, who's still there, and your own personal preference. I always like to try to get two RB's with my first 3 picks, but if you can get 2 stud WR's (or like the discussion above, if an elite QB- Brees, Rodgers, or Manning- is still there, that's another good option) Just make sure you feel good about the first 3 guys you take. After that, you need to start looking at what's left in the positions you haven't filled yet. For example, if you go RB-WR-WR with your first 3 picks, you have to start thinking about targeting a QB and another RB the next time it comes around to you. Then again, if you're not thrilled with anyone at those positions, but there's still a TE you covet, maybe grab him while you can. Just don't wait too long to get that 2nd RB or 2nd or 3rd WR, because after a while, you'll be digging through scraps. Same goes with QB's- as much as I advocate waiting and trying to get a good value pick later, don't wait too long. I'd say grab one by round 5 at the latest.
Oh, one more thing. Once you're past round 3, and it's coming back the other way in round 4, start taking note of what positions the guys picking 1-4 need. If they all have QB's already, there's no need to use your 4th round pick on a QB, since they're not likely to take another one at that point. On the other hand, if there's only one or two QB's left that you'd really like, and two of those guys don't have one yet, grab yours before they pick. Same goes if they need WR's or RB's; take into consideration what positions they're likely to go for and what that will leave you with.