If Night Dive could get their hands on the source code for D2 though, wouldn't it be possible to do a port to PC? It'd be a bit more involved than a DOSBox wrapper for a game, but they've updated code before.
Night Dive is looking to "remaster" System Shock by moving all the game assets to the Unity engine. They're looking to launch a Kickstarter to fund it:
A Kickstarter to port D2 could be done, although I don't know if that title has the same fanbase and brand awareness as System Shock.