Uchiha
Hyuga
Akimichi
Aburame
I think those are the noble clans, but if your going by who was there in the beginning Senju and Uchiha are the founding clans
Also"The war has already begun… My name no longer matters. You can call me by my old name, Tobi, if you prefer. Madara, Tobi… call me whatever you want. I'm no one".