[quote name='RedvsBlue']Nah, your just pissed cause I hit too close to the truth. Your girlfriend's gonna end up being a crazy bitch again and your cheap Gamecube's gonna end up crappin' out on you as well. Face it, you're screwed in life and your "give me advice" threads.[/quote]
While I have no idea what thread you're talking about, and I don't usually like to pick sides in an argument I'm not involved in, I have to say that asking opinions on relationships and cleaning a system are quite different. Telling somebody "don't go out with somebody you care about," while sometimes the best advice, isn't exactly the same as letting somebody know the best way to clean up a system so that it looks and plays like new.
As for your cleaning problem, I'd say go with the soap and water that someone suggested. Should kill all the germs and remove any smudges you've got. If you really want to clean it out, you could always take the top off and dust/use canned air as somebody else suggested. It's really quick and easy to take the cover off (assuming you have the correct tools needed), and shouldn't take you any more than 5 minutes to take it off and put it back on.