I have donated a ton of clothes and other things to Goodwill over the years. I've never bothered with the deductions as I've never had enough things to do an itemized tax return.
I just use it to get rid of stuff everytime I move. Clothes, pots and pans I don't want to take with me, DVDs I've upgraded to blu ray or just will never watch again, books etc. Easier to just donate them than hassle trying to sell them since most of them wouldn't get more than a couple bucks in a yard sell etc. anyway.
Actually have another bag of clothes, a couple of DVDs and an extra Brita filter that I need to donate currently.