(In response to... basically everyone

)
My friend tried the game, and he didn't run into any issues. idk, I think I'm just cursed or something - I always seem to run into computer problems (and, no, I'm not retarded when it comes to computers - I'm just unlucky!) Here are the issues I personally ran into on a fully patched version of Mass Effect:
1. With hardware audio enabled, sounds would randomly not play. I tried it both on my integrated audio and on my X-Fi Titanium, and I ran into it on both. Funny that it says it works best on X-Fi...
2. Random crashes - I remember for a fact that I got a crash to the desktop due to a missing audio file.
3. Stopped responding to keyboard input - It just randomly stopped responding to my keyboard after exiting the map.
4. Therum was missing almost all textures (making it unplayable). This was supposed to be fixed in 1.1, but I had to install the DLC (which includes the 1.1 patch) to fix it. Apparently 1.1 doesn't mean 1.1...
5. Random freezes - The game liked to randomly freeze for a few seconds at a time. Really annoying.
6. I'm not 100% sure on this, but even on the easiest setting, this game seemed like it was running on the hardest setting. The funny part is, I played it on the normal setting on 360, and it seemed a heck of a lot easier. It almost seemed like the PC version was stuck on the hardest setting or something - I actually used a hex editor to view my saved game file, and, if I recall, changing the difficulity didn't seem to have any affect on the saved game file.
Hey, if the PC version works for you, more power to you - I'm just saying, I personally had nothing but problems with it.
Completely off topic, this is the game that finally made me say "

it" to PC gaming (well, this, and multiple other crappy console ports). It's too bad, since I have a really nice PC - it's just not worth the effort anymore. Sure, maybe consoles don't run at 1080p with 16x AA, but the games actually work!