If you enjoy/like the following, then yes:
Science-fiction
Epic story that spans the galaxy
Third person shooters
Having consequences to your actions
Having decisions/consequences carry through to sequels
If you enjoy all of these, then by all means, get it.
Also, something to note:
ME1 is technically inferior (I think it's the absolute worst game this generation, from a purely technical standpoint). When I say that, I mean it has frame rate issues, crashes, glitches, texture loading, and more up the ass. But, don't let this stop you from playing it. The interaction and story are excellent. They easily outweigh the many technical issues plaguing the game.
The best part is that it only gets better from there with ME2. My personal favorite, I find it to be the most balanced and well-rounded of the three. Excellent gameplay, graphics, sound, and now, with fewer bugs/glitches. The story is straightforward, but the real heart of the story lies with your squad.
As for ME3, well...you'll have to form your own opinion (I don't doubt you've heard quite a bit about the ending). Gameplay, graphics, and sound wise, it's quite excellent. Story wise? I'd say it's pretty good (aside from a VERY jarring shift in main antagonist) until the last 15 mins. The final 15 mins will probably piss you off, if you're invested in the story. Also, before playing ME3, download the Extended Cut. Do not play the ending without it.