Yes and yes and it depends.
The transmitter box has both optical and stereo RCA inputs, so just about any device can be plugged into it with the right cables, so it definitely is versatile. But while I haven't used this headset myself, I've found that IR sound transmitters are quite finicky in terms of quality. If you use it in a room with a lot of other electronics, you will likely hear a bit of interference during quiet moments.
However, because you have a PS3 you'd probably be better served with the Tritton AX pro, which is also capable of voice chat on the PS3 and PC, via USB (the X4 can only chat on the 360). It's also about thirty to fourty bucks cheaper. It's only downsides are that it's wired (but a hefty 12.5 feet of it), uses two medium size AC adaptors (making it a bit of a bear to setup at first, but doesn't require batteries), and can ONLY accept optical audio, or PC 5.1 (which limits what can be used with it, but not by a whole lot).
Another model to look up is the Astro A40, which I don't know a whole lot about. But it's $250, so I quickly passed on it.
It's worth looking up all of these to see which one would suit you best.
I can't speak for the all important audio quality of any of these, but I recently ordered the AX pro, and I actually plan on doing a video review of it when CheapyD posts his review of the X4.