This is kind of an interesting (sad) story.
I got my PS2 on release day, but since I was just getting back from a business trip from Japan a buddy picked it up. As I didn't have any games that day, my wife (girlfriend then) decided to play some PS1 games. I thought some Need For Speed, Hot Pursuit would be fun.
I popped the game in and we started a race. By the end, my wife turned several shades of green and was sick. That was the first we found out that she can't watch or play many video games. She's fine, but we have found that many games cause her to have a very bad reaction.
As a result, we don't get to play many games together anymore (hence, the sad part).
We do play some Guitar Hero, but my wife really hates Rock Band, so that's about it.
TBW