[quote name='n25philly']maybe x64, but 99% of game play perfect on the 32 bit version[/QUOTE]
This is true. I've been using Vista since the beta, and I've had only a few problems that were mostly due to driver issues. I do have a few games that don't work on Vista though; one being Manhunt, unless you disable DEP.
I've had almost no problems with programs, because I keep them up to date.