I complained about this game over in the flyers thread, but thought I'd re-iterate some of it here, and hopefully keep some of you from wasting your time and money...
I had the game lock up on me around a dozen times (although, that was over the course of 90-some hours...). I also hit a couple of bugs that wouldn't let me complete quests, and one where one of my followers got stuck in an unbreakable dialogue loop with an intercom --- even if I knocked her unconscious and pushed her into another room, when she woke up, she'd run right back to the intercom... Obviously can't speak to the latest patch, but even after the 1.2 patch, the game was still buggy.
Bugs and glitches aside, the game was kind of enjoyable for the first 10-15 hours or so, then turned into a mind-numbing slog of snooze-riffic proportions... If it weren't for those damned achievements, I'd have given up shortly after I made it to New Vegas...