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Set seven years after the episodes of Cole MacGrath, Seattle has been locked down by the Department of Unified Protection (DUP), an organization that handles any sort of bio-terrorism to ensure that the events of Empire City and New Marais don't repeat themselves. It was revealed that the DUP renamed Conduits to Bioterrorists and have been rounding them up, jailing them and possibly killing them. It was also revealed that the developers assumed the good ending of InFAMOUS 2 as canon and that, rather than the RFI destroying all conduits, some survived based on their resistance to its effects and distance from New Marais.
The game is set in Seattle, Washington, now under DUP jurisdiction. Players control Delsin Rowe a 25-year-old graffiti artist with no real direction in life. One day, Delsin witnesses a bus crash and attempts to help; in the process, he comes in contact with a Conduit, and his own hidden Conduit abilities awaken. With his new abilities and his older brother Reggie, a police officer, Delsin dedicates himself to fighting back against the oppressive DUP, as well as other Conduits such as Abigail "Fetch" Walker. In an interview, it was stated that for InFamous fans there would be a few familiar faces in the game, but it 'would ruin the joy of discovering them' to reveal exactly which known characters will be present in Second Son.
https://www.youtube.com/watch?v=MlNfJvFnzc8

https://www.youtube.com/watch?v=o-B40rzJHOY
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