I ate some homemade hotsauce that my Pakistani friend's dad made. One teenage kid who was eating with us started crying. My mouth was on fire, tongue hurt, and the aftermath in the toilet wasn't pleasant, but I was a trooper and finished it off. It was delicious, but painfully hot.
I remember my worst experience with peppers though. Can't remember the variety, but I was cutting them up to cook with, and washed my hands about ten times, knowing that I had the oils all over them. About four hours later, I'm sitting on the couch playing videogames, put my hand down my pants to scratch my nuts, and BLAMMO...apparently the oils were still on my hands. You have not experienced fear and pain until you have hot pepper burning your ball sack. My wife laughed until she could tell I wasn't joking around anymore. Water, ice, air. It didn't really matter. Just had to wait it out.
I cut hot peppers with gloves on now.