Like
Left 4 Dead, the sequel involves the aftermath of an
apocalyptic pandemic. There has been an outbreak of a
rabies-like
pathogen that causes infected humans to behave like
zombies. The four survivors have to fight their way through the hordes of infected, using safehouses along the way to rest and recover, in order to reach extraction points.
Left 4 Dead 2 is set in the
Southern United States, starting in
Savannah,
Georgia and ending in
New Orleans,
Louisiana.
[3][4] Left 4 Dead 2 introduces four new survivors, whose backstory is again provided through dialogue. Unlike the first game where there was no significant story development,
Left 4 Dead 2 features a story arc.
[7]
After climbing a hotel in Savannah to achieve rescue, the survivors find themselves abandoned by helicopters, and make their way to the local mall after hearing word of a second evacuation point there ("Dead Center"). The mall proves to be overrun, and the four use a
stock car to bust out of the mall and travel towards New Orleans. Finding the highway completely blocked by wrecked vehicles, the four are forced to travel through a still-operating amusement park, and start a huge fireworks-and-lights show in order to attract the attention of a helicopter pilot ("Dark Carnival"). Though rescued, they find their pilot to have been infected, and are forced to kill him, causing the helicopter to crash into a
bayou ("Swamp Fever"). Finding brief shelter in a plantation mansion, they make radio contact with a boat captain named Virgil who rescues them, but informs them that he needs additional diesel fuel to make it to New Orleans. Amid a torrential downpour, the survivors go ashore, make their way to a gas station to get fuel supplies, and return and defend their position while waiting for the boat ("Hard Rain"). Virgil takes them to New Orleans, where the military appears to still be evacuating survivors, but as they make their way to the extraction point, they find that the military is actually bombing the city to cleanse the infection ("The Parish"). They are able to clear the bridge amid a mass of infected and reach safety, moments before the bridge is demolished.