You know what's missing from this game? Groin shots. In Fallouts 1 and 2, you could target the junk, which would usually knock enemies down, or unconscious. (You could also target the eyes for massive damage, and blinding opponents)
One other minor quibble: I think Bethesda missed the point of Tagging skills. In 1 and 2, in character creation, you tag a skill, you get a bonus to the skill, same as 3. When you level up in 1 or 2, a tagged skill means that every skill point you allocate adds 2 percent (instead of one, natch). Like I said, minor thing.
I'm seriously digging the hell out of this game.