With all due respect to you Star Trek Scholars here, you're trying to make the situation more black and white than it actually is..no one person ruined Trek.
Star Trek is where it is today because the world, including Trek fans, is burned out on seeing the exact same plotlines played out over and over with every new series. The stories were always the same. Enterprise was doomed from the start............it was clearly a cash-in show. Poor writing, and shoving a vulcan on board immediately and making her a sex kitten was a hugely bad idea....of course to Paramount, 7 of 9 "saved Voyager" so lets get a head start right?
Roddenberry was a good visionary, but his early seasons of TNG are just ToS with new actors and bad cgi, the stories are all simple, always involve "Oh the bad guy isn't bad at all, he's just misunderstood!". Kinda like ToS.
After Roddenberry relinquished control the Paramount guys at least gave the show the edge it needed to remain interesting. But, like all good teams, they eventually ruined the property for the time being by giving us too much too soon with not enough thought put into what bigger story are they trying to tell.
Voyager was the only show I actually dis-liked. Even in the later episodes, it became "just another Trek show". They never capitalized on the "survival horror" aspect of being a ship a gajillion miles from home...it was just "Gee, we're never getting home but everything here is the same as it is back home so big whoop".
Enterprise, i watched like 2 episodes of and never went back.....it was truly a bad show....
For my money, its ToS then DS9 then TNG....and then the alsorans.