Dead Space looks cool. I wish I had a better setup to play it though. I'm in the basement with an old HDTV that has a 4 inch dark spot on the bottom, no surround sound, horrible seating (I'm sitting on an outside swinging bench with a pillow tied to it), and it is freezing because the floors are concrete with no carpet. Upstairs there is a 50" 1080p set, 7.1, and a couch mocking me. Therefore, I'm going to skip it. If my parents go away or something for a weekend and I don't have to work much I'll rent it and get my fix then.
I have a similar situation with my computer being in the kitchen so I had the same problem with BioShock. The experience just isn't the same and I couldn't get into it.