I've got a problem with 5.1 in Lost Odyssey. In certain types of cutscenes, it sounds like the dialog is only coming out of the left front speaker, instead of left and right. If I get close to the right speaker, I can hear the music, and the dialog is playing, but very low.
The fancy CG cutscenes sound fine, and the voice that comes out when in-game sounds fine, it's the cutscenes in between these that sound wrong. Anyone else have this problem? I think the same thing was happening in Eternal Sonata, but I was playing the PS3 version so I can't blame it on either system.