Shacknews.com gave Mass Effect 2 their RPG of the year award for 2010:
http://www.shacknews.com/onearticle.x/66961
For the link lazy:
[quote name='Shacknews article']
In the far reaches of space, one man (or woman, if you'd prefer) holds the key to the salvation and preservation of the human race. In Mass Effect 2 players are introduced to a host of new characters that fight alongside Commander Shepard. While Shepard can be crafted to be as good or as bad as you want him or her to be, the character manages to remain a completely memorable figure in the world of video games for what he or she is able to accomplish.
It may be spoilerish to say (although, it happens within the first five minutes of the game), Shepard literally comes back to life and with him a completely new experience is born. Throwing out much of the original title's gameplay, Mass Effect 2 turns into an intense shooting experience with a focus on telling an incredible story, rather than spending hours buried within menus. Not only is Mass Effect 2 the best role-playing game to come out of 2010, it may be one of the best role-playing titles ever developed.[/quote]
It also picked up a runner-up award for Best Story of 2010, behind Red Dead Redemption:
http://www.shacknews.com/onearticle.x/66954
Link-lazy:
[quote name='Shacknews article']From the moment it begins, it was clear that BioWare was holding no punches in terms of the story of Mass Effect 2. Including everything--and a few space-age kitchen sinks--Mass Effect 2 ties up loose ends from the original (if you completed that quest), introduced fantastic new characters, and revealed the war of good versus evil is muddled with as many gray spots on land as they are in the stars. Although it may be forgotten since it launched in January, Mass Effect 2 was one of the finest games to launch in 2010[/quote]
And yet another award, Best Magic Moment of 2010:
http://www.shacknews.com/onearticle.x/66942
Link-lazy, again:
[quote name='Shacknews article']We do lots of different things in video games but every so often we find ourselves, controller in hand, experiencing one of those "this is why I play video games" moments. In 2010, the best of these came while directing Commander Shepard through conversations in Mass Effect 2. A refined version of the system in the first game, it perfected the ability to naturally guide the course of conversations being held by the characters without having to break and reason out long passages of dialog to select between. Coupled with greatly improved staging of the scenes and more cinematic camera angles, it became almost impossible not to get completely wrapped up in Shepard's saga.[/quote]