[quote name='Vinny']It's only 50K? Are you serious?[/quote]
Of course. I don't have a link offhand, but about a year ago, the Japanese financial group Nikkei worked out that the average PS2 game needed to sell 50,000 copies to break even, while the average PS3 game needed to sell 500,000 copies due to the greater expense of HD assets and whatnot.
Since the Wii is closer to the PS2 in regards to performance and graphics, it's not a stretch to say that a Wii game will break even around 50,000-100,000 copies sold -- and anything higher than that (200K+) would be considered pure profit.
I have no idea how Capcom's numbers are for Zack and Wiki, but if they sold 250,000 copies (out of the 300,000 copies shipped), and they noticed all the glowing reviews it got, I'm hoping they will be motivated to put in a bit more effort for a sequel and try to turn it into a franchise.
--R.J.