The NBC broadcasts of Chuck are some of the very worst "High Definition" I've ever seen. The show has really bad, ugly photography caked in layers and layers of grain. It's soft and dupey, and often doesn't look better than VHS quality.
The Blu-ray will probably rectify some of NBC's macroblocking and motion artifact problems, but I wouldn't hold out hope for a stunning "eye candy" presentation.
And Chuck has really bad photography for a show on any major network. It's shot on 16mm, but that's not the crux of the problem.