I am listening to Cagcast #194. Glad to hear that adventures cross your desks a little more than usual. That's one of the most interesting differences concerning perspective. Where I live, in Germany, adventures exist, and do quite well, reaching the top charts position. I am happy to say that I work for a big adventure right now as composer and sfx designer. That studio got the best studio of 2009 developer award here in Germany, their last game was Top 5, so it's not dead at all here.
Secret files: Tunguska which Wombat mentioned is one of the best-selling adventures in the last years in Germany. It's a very good game I think. Realistic thriller-esque with some humor.
And, you said a Sherlock Holmes adventure would be nice: Did you know, there are half a dozen Sherlock Holmes games out for the PC, the latest one even for Xbox
http://marketplace.xbox.com/en-GB/games/media/66acd000-77fe-1000-9115-d802464507d3/ Those games are far from perfect but quite stylish, I recommend The Awakened, that's Sherlock Holmes vs. Cthulhu!
AND best of all, a few classic games are out for your Iphone: Beneath a Steel Sky, Monkey Island 1, Simon the Sorcerer, Broken Sword...
Also, just another quick note, people still play PC games here. And Germany's among the top 5 of global games markets. Yes, everyone is angry here about that PC - Assassins Creed disaster, still I had to frown when Wombat asked a few shows back why the hell they made a PC version at all.
So, I sometimes sigh when I hear international podcasts talk about PC games as unrelevant and adventures as dead. Glad that the last part seems to change a little at least, with Monkey Island on the Wii and all.
Sorry, not a question really, but maybe this qualifies as input of SOME sort. That's all I got. Cheers, keep up the good work.