After two quick games on All-Pro this is how I feel -
Speed kind of feels like speed. To me, guys with 'get away from the cops speed' should blow by defenders, but they rarely do it. Part of that I think is perception, 6 yards IRL is a lot farther than 6 yards in Madden.
I really like the organic feel of the physics engine. I only saw a few weird (and often hilarious) collisions. In one replay Matt Flynn was giving Fletcher a hardcore blowjob!
Sydney Rice made a stupid, one handed catch and Mike Williams tipped the ball up, ran 5 or 6 yards and caught it. Both of those plays made me sick, but I suppose they are possible, hopefully they don't happen all the time. The picks I threw were my own fault, for once!
On defense I still don't think the edge rushers in the 3-4 get enough pressure. I agree with Doom that usering seems to be a step or two behind, though that might be a recationary thing.
Graphics/Presentation is pretty nice. I didn't see any 'jaggies' like in NCAA 13 and the framerate barely dropped at all. Once thing I didn't like was lighting. Depending on where the light source is the entire defense looks like black blobs because of the shadowing. Oh, and commentary was not existent until I paused the game in the middle of Q2. That happened to me all the time in M12, looks like that bug is still there.