- All 493 Pokemon can follow you around
- talk to Pokemon to see how they feel about you
- The PokeDex, Computer Boxes and your bag have gotten a new layout
- revisit Kanto to check out new locations
- You must have your "Pikachu Coloured Pichu" following you in Ilex forest to activate the Notched Eared Pichu event
- Pre-order HeartGold and get a Ho-Oh figure, pre-order SoulSilver and get a Lugia figure, pre-order both and get both figures and an Arceus one.
- Jirachi - level 5, Draco Meteor, Rest, Wish and Confusion, holding a Liechi Berry
- Kyogre appears in Heart Gold
- Groudon appears in Soul Silver
- bring the two together to get Rayquaza
- Cynthia appears in the remakes when the Arceus event is activate